Impact of long-term epidural electrical stimulation enabled task-specific training on secondary conditions of chronic paraplegia in two humans

L Beck, D Veith, M Linde, M Gill, J Calvert… - The Journal of Spinal …, 2021 - Taylor & Francis
… LT was followed by implantation of a 16-contact epidural … and 12 months of EES enabled
task-specific training, which we termed … Prior to enrolling the second participant, additional body …

Beneficial cardiac structural and functional adaptations after lumbosacral spinal cord epidural stimulation and task-specific interventions: a pilot study

BE Legg Ditterline, S Wade, B Ugiliweneza… - Frontiers in …, 2020 - frontiersin.org
… , the stimulation amplitude was low to enable proprioception to … This beneficial adaptation
has implications for long-term … to decrease the secondary health consequences of spinal …

Insights on the potential mechanisms of action of functional electrical stimulation therapy in combination with task-specific training: a scoping review

JC Furlan, M Pakosh, BC Craven… - … : Technology at the Neural …, 2022 - Elsevier
… of minimizing the effects of the cascade of secondary injury (eg… in combination with epidural
electrical stimulation. Those … The results of this review suggest that electrical stimulation

Structural and Functional Myocardial Adaptations to Task-Specific Epidural Stimulation in Chronic Spinal Cord Injury.

HD Ledbetter - 2022 - ir.library.louisville.edu
… The second aim of the study is to compare long-term cardiac effects of cardiovascular
scES … Altering spinal cord excitability enables voluntary movements after chronic complete …

[HTML][HTML] Targeting lumbar spinal neural circuitry by epidural stimulation to restore motor function after spinal cord injury

K Minassian, WB McKay, H Binder, US Hofstoetter - Neurotherapeutics, 2016 - Elsevier
… volitional control enabled by epidural stimulation in otherwise … SCI are able to generate
task-specific EMG activity. Instructed to … Long-term control of spasticity was achieved soon after …

Epidural electrical stimulation: a review of plasticity mechanisms that are hypothesized to underlie enhanced recovery from spinal cord injury with stimulation

JT Eisdorfer, RD Smit, KM Keefe, MA Lemay… - Frontiers in Molecular …, 2020 - frontiersin.org
… we hypothesize may enable epidural stimulation to promote … underlie EES-induced long-term
recovery remain elusive. It is … ); and (3) identification and subsequent tracing of secondary

Electrical stimulation and motor recovery

W Young - Cell transplantation, 2015 - journals.sagepub.com
… and peripheral electrical stimulation improve long-term motor (90) … epidural cortical stimulation,
epidural spinal stimulation, and … training, repetitive pattern motor activity, and task-specific

… Participants With Chronic Clinically Motor Complete Spinal Cord Injury: Restoration of Rehabilitative Function With Epidural Spinal Stimulation (RESTORES) Trial—A …

KR Wan, ZYV Ng, SK Wee, M Fatimah, W Lui… - Journal of …, 2024 - liebertpub.com
… assistance during each task-specific training, thus … Long-term spinal cord stimulation after
chronic complete spinal cord injury enables volitional movement in the absence of stimulation

Epidural spinal cord stimulation as an intervention for motor recovery after motor complete spinal cord injury

JT Hachmann, A Yousak, JJ Wallner… - Journal of …, 2021 - journals.physiology.org
Secondary findings also included improvements in blood … signals, epidural stimulation may
enable task-specific volitional … The long-term effects of prolonged periods of inactivity may …

[PDF][PDF] Task and physiological specific stimulation for recovery of autonomic function, voluntary movement and standing using epidural stimulation and training after …

I Overall - classic.clinicaltrials.gov
… that epidural stimulation and task-specific training will … In a secondary study we will evaluate
the effect of these 4 … We provide a cellular environment that enables sensory-motor and …