Improvement of a rapid direct blood culture microbial identification protocol using MALDI-TOF MS and performance comparison with SepsiTyper kit
F Di Gaudio, S Indelicato, S Indelicato… - Journal of …, 2018 - Elsevier
Fast diagnosis of pathogens is critical to guarantee the most adequate therapy for infections;
bacterial culture methods, which constitute the actual gold standard, are precise and
sensitive but rather slow. Today, new methods have been made available to enable faster
diagnosis, with the Matrix-Assisted Laser Desorption Ionization–Time Of Flight Mass
Spectrometry (MALDI-TOF MS) technique being the most promising. Even if simpler and
faster than traditional bacterial culture methods, analysis of positive blood cultures via …
bacterial culture methods, which constitute the actual gold standard, are precise and
sensitive but rather slow. Today, new methods have been made available to enable faster
diagnosis, with the Matrix-Assisted Laser Desorption Ionization–Time Of Flight Mass
Spectrometry (MALDI-TOF MS) technique being the most promising. Even if simpler and
faster than traditional bacterial culture methods, analysis of positive blood cultures via …
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