Improving cellulase productivity of Penicillium oxalicum RE-10 by repeated fed-batch fermentation strategy

X Han, W Song, G Liu, Z Li, P Yang, Y Qu - Bioresource technology, 2017 - Elsevier
Medium optimization and repeated fed-batch fermentation were performed to improve the
cellulase productivity by P. oxalicum RE-10 in submerged fermentation. First, Plackett-
Burman design (PBD) and central composite design (CCD) were used to optimize the
medium for cellulase production. PBD demonstrated wheat bran and NaNO 3 had significant
influences on cellulase production. The CCD results showed the maximum filter paper
activity (FPA) production of 8.61 U/mL could be achieved in Erlenmeyer flasks. The maximal …

Improving cellulase productivity of Penicillium oxalicum RE-10 by repeated fed-batch fermentation strategy.

HXL Han XiaoLong, SWX Song WenXia… - 2017 - cabidigitallibrary.org
Medium optimization and repeated fed-batch fermentation were performed to improve the
cellulase productivity by P. oxalicum RE-10 in submerged fermentation. First, Plackett-
Burman design (PBD) and central composite design (CCD) were used to optimize the
medium for cellulase production. PBD demonstrated wheat bran and NaNO3 had significant
influences on cellulase production. The CCD results showed the maximum filter paper
activity (FPA) production of 8.61 U/mL could be achieved in Erlenmeyer flasks. The maximal …
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