Objectives: Upper airway injury is a recognized complication of prolonged endotracheal
intubation, yet little attention has been paid to the consequences of laryngeal injury and
functional impact. The purpose of our study was to prospectively define the incidence of
acute laryngeal injury and investigate the impact of injury on breathing and voice outcomes.
Design: Prospective cohort study. Setting: Tertiary referral critical care center. Patients:
Consecutive adult patients intubated greater than 12 hours in the medical ICU from August …