过去一年中添加的文章，按日期排序
Genome-Scale CRISPR Screens Identify Novel Genes That Regulate Erythropoietin Production and Secretion
Z Lin - 2024 - deepblue.lib.umich.edu
15 天前 - … The left column represents gene expression levels under normoxia, and the …
induced by hypoxia due to increased stability of the transcription factor hypoxia-inducible factor …
induced by hypoxia due to increased stability of the transcription factor hypoxia-inducible factor …
CBX7 promotes choroidal neovascularization by activating the HIF-1α/VEGF pathway in choroidal vascular endothelial cells
Q Wang, M Zhu, W Li, Y Guo, H Lou, J Zhang… - Experimental Eye …, 2024 - Elsevier
29 天前 - … CBX4 enhances hypoxia-induced VEGF expression and … an epigenetic reader to
control gene expression. This family can be … A transcription factor called HIF-1α accumulates in …
control gene expression. This family can be … A transcription factor called HIF-1α accumulates in …
49 Inhibition of AXL along with c-Met potentially halts resistance development in renal cell carcinoma
47 天前 - … , Hepatocyte Growth Factor (HGF), c-Met activates pro-… Interestingly, c-Met
inhibitor(s)induced overexpressed c-… genes associated with glycolysis, angiogenesis, hypoxia, …
inhibitor(s)induced overexpressed c-… genes associated with glycolysis, angiogenesis, hypoxia, …
Transforming the management of chronic kidney disease-associated anemia using daprodustat
II Raza, S Younus, H Azhar, H Fatima… - Annals of Medicine …, 2024 - journals.lww.com
125 天前 - … mediators in CKD also inhibit hypoxia-induced EPO gene activation. One of these
… -β heterodimer activates EPO gene expression by binding to DNA sequences called hypoxia …
… -β heterodimer activates EPO gene expression by binding to DNA sequences called hypoxia …
Hif-1α expression targets the TMA/Fmo3/TMAO axis to participate in gallbladder cholesterol stone formation in individuals living in plateau regions
M Luo, P Chen, Y Tian, N Rigzin, J Sonam… - … et Biophysica Acta (BBA …, 2024 - Elsevier
151 天前 - … Hypoxia and lithogenic diet induce the expression of Hif-1α, … and transcription
factor Hif-1α binding site, the mRNA and … (B) mRNA expression of genes related to cholesterol …
factor Hif-1α binding site, the mRNA and … (B) mRNA expression of genes related to cholesterol …
The MET Oncogene: Thirty Years of Insights into Molecular Mechanisms Driving Malignancy
T Crepaldi, S Gallo, PM Comoglio - Pharmaceuticals, 2024 - mdpi.com
174 天前 - … The identification of MET as the hepatocyte growth factor (HGF) … Hypoxia is one
condition that induces MET transcription [90]. … Gene expression is not solely governed at the …
condition that induces MET transcription [90]. … Gene expression is not solely governed at the …
c-Met/AXL crosstalk in mediating therapeutic resistance in renal cell carcinoma
182 天前 - … specific ligand, Hepatocyte Growth Factor (HGF), c-Met activates pro-tumorigenic …
) induced c-Met and AXL overexpression in RCC cells. Interestingly, c-Met inhibitor(s)-induced …
) induced c-Met and AXL overexpression in RCC cells. Interestingly, c-Met inhibitor(s)-induced …
[HTML][HTML] Immunopathogenesis of liver fibrosis in steatotic liver disease
C Woo, WI Jeong - Clinical and Molecular Hepatology, 2024 - ncbi.nlm.nih.gov
213 天前 - … and liver, in which hypoxic adipocytes excreted glutamate … (MPO), transforming
growth factor (TGF)-β1, and ROS by … + CD11b + macrophages can induce fibrosis resolution by …
growth factor (TGF)-β1, and ROS by … + CD11b + macrophages can induce fibrosis resolution by …
Secretome of Hypoxia-Preconditioned Mesenchymal Stem Cells Promotes Liver Regeneration and Anti-Fibrotic Effect in Liver Fibrosis Animal Model.
F Amansyah, B Budu, MH Achmad… - Pakistan Journal of …, 2024 - europepmc.org
264 天前 - … examine the cytokines and growth factors present in both … examination and analysis
of mRNA expression. <b>Results:</… >-induced liver fibrosis and decrease α-SMA and TGF-β …
of mRNA expression. <b>Results:</… >-induced liver fibrosis and decrease α-SMA and TGF-β …
The role and mechanism of HIF-1α-mediated glypican-3 secretion in hypoxia-induced tumor progression in hepatocellular carcinoma
P Wang, K Tong, Y Li, X Li, Y Zhang, J Gu, P Lei… - Cellular …, 2024 - Elsevier
286 天前 - … activates downstream genes through hypoxia-inducible factor 1-alpha (HIF-1α),
which promotes the growth … tumor-suppressor genes by activating HIF-1α [11]. We found that …
which promotes the growth … tumor-suppressor genes by activating HIF-1α [11]. We found that …