[PDF][PDF] Infliximab therapy in pulmonary fibrosis associated with collagen vascular disease

KM Antoniou, M Mamoulaki, K Malagari… - Clinical and …, 2007 - academia.edu
KM Antoniou, M Mamoulaki, K Malagari, HD Kritikos, D Bouros, NM Siafakas, DT Boumpas
Clinical and experimental rheumatology, 2007academia.edu
… In this report we describe the use of the anti-TNF-α monoclonal antibody, infliximab, in
three patients with RA and one woman with systemic sclerosis and pulmonary fibrosis. …
Our data indicate that infliximab may be a useful treatment in pulmonary fibrosis associated
collagen vascular disease. Randomized-controlled clinical trials are required for the better
evaluation of this agent in the treatment of these patients. …
Objective
To study the potential effectiveness of tumor necrosis factor α (TNF-α) inhibitor treatment for pulmonary fibrosis associated with a collagen vascular disease, CVD (rheumatoid arthritis, RA and systemic sclerosis, SSc) refractory to conventional treatment.
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