Background Data on influenza burden in risk groups for severe influenza are important to
guide targeted influenza immunization, especially in resource limited settings. However, this
information is limited overall and in particular in low-and middle-income countries. We
sought to assess the mean annual national burden of medically and non-medically attended
influenza-associated mild, severe-non-fatal and fatal illness among potential target groups
for influenza immunization in South Africa during 2013–2015. Methods We used published …

Background Data on influenza economic burden in risk groups for severe influenza are
important to guide targeted influenza immunization, especially in resource-limited settings.
However, this information is limited in low-and middle-income countries. Methods We
estimated the cost (from a health system and societal perspective) and years of life lost (YLL)
for influenza-associated illness in South Africa during 2013–2015 among (i) children aged 6–
59 months,(ii) individuals aged 5–64 years with HIV, pulmonary tuberculosis (PTB) and …