Inhibition of doxorubicin-induced mutagenicity by Baccharis dracunculifolia

FA Resende, JM Alves, CC Munari… - … /Genetic Toxicology and …, 2007 - Elsevier
Baccharis dracunculifolia DC (Asteraceae), a native plant from Brazil, have been used as an
antipyretic, stomachic and health tonic in Brazil. The objective of the present study was to
investigate the potential mutagenic effect of B. dracunculifolia ethyl acetate extract (Bd-EAE)
and its influence on the mutagenicity induced by the chemotherapeutic agent doxorubicin
(DXR) using the rat bone marrow and peripheral blood micronucleus test. Wistar rats were
divided into 10 treatment groups. Five groups received DXR (90mg/kg body weight, bw …
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