过去一年中添加的文章,按日期排序

Screening potential antileukemia agents from duckweed: Integration of chemical profiling, network pharmacology, and experimental validation

J Liu, M Huang, Y Yang, Y Zeng, Y Yang… - Phytochemical … - Wiley Online Library
2 天前 - … flavonoids may offer new insights into the search for novel drugs to treat AML. …
triggered by apiin and luteoloside treatment, we used Z-VAD, a caspase inhibitor, to restore the …

BENEFICIAL EFFECTS OF PURPLE POTATO ON GASTROINTESTINAL HEALTH

Q Sun - rex.libraries.wsu.edu
2 天前 - methods, vacuum-sealing and boiling exhibit the highest content of extractable
polyphenolic compoundsInhibition of PGC-1α by either inhibitor or siRNA knockdown negated …

The Potential of Compounds Derived from Jatropha Curcas Against Pr and Herα in Breast Cancer Treatment: Molecular Docking and Molecular Dynamics Simulation …

E Kitete Mulongo, J Kilembe Thambwe, A Matondo… - papers.ssrn.com
2 天前 - … Breast cancer remains the most common cancer to date. This study aims to evaluate
… of bioactive compounds identified within Jatropha curcas using in silico methods. Two …

Rhodiolin inhibits the PI3K/AKT/mTOR signaling pathway via the glycolytic enzyme GPI in human papillary thyroid cancer

J Bo, S Mao, J Yang, L Wang, J Zheng, C Zhang… - Phytomedicine, 2024 - Elsevier
2 天前 - Methods … To identify safer and novel inhibitory drugs for PTC, we undertook
high-throughput screening of a well-characterized library of NO-SMCs. We explored the inhibitory

[HTML][HTML] The causal relationship between anti-diabetic drugs and gastrointestinal disorders: a drug-targeted mendelian randomization study

M Ju, T Deng, X Jia, M Gong… - Diabetology & …, 2024 - dmsjournal.biomedcentral.com
2 天前 - … primary analytical method to assess the impact of these inhibitors on gastrointestinal
inhibitors, DDP-4 inhibitors, Insulin and its analogs, Thiazolidinedione, and other drugs did …

Identification of metastasis-related genes for predicting prostate cancer diagnosis, metastasis and immunotherapy drug candidates using machine learning …

YX Wang, B Ji, L Zhang, J Wang, JX He… - Biology …, 2024 - pubmed.ncbi.nlm.nih.gov
2 天前 - method, which were found to be associated with DNA damage, hormone AR activation,
and inhibition of the … of immunotherapy and targeted therapy drugs. A diagnostic model …

UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL

R Zhang, C Li, S Zhang, L Kong, Z Liu… - Clinical and … - pubmed.ncbi.nlm.nih.gov
2 天前 - Methods: Cox and LASSO regression analyses were … compound that inhibits
the expression of UBE2S, and PX-478, an inhibitor of HIF-1α, significantly improved the anti-tumor

Synthesis and Characterization of Newly Phthalocyanine Molecules: Their Enzyme Inhibition and Antioxidant Properties, In silico and in vitro

F Çelik, Y Ünver, F OzTuncay, U Cakmak… - Journal of …, 2024 - Elsevier
2 天前 - Compound (6b) showed inhibitory activity on amylase … Finally, the inhibition properties
of these molecules on the … docking method, which is a computer-based research method. …

Immunosuppressive drug and cancer risk

S Karmore, G Mude, P Date - Multidisciplinary Reviews, 2024 - malque.pub
2 天前 - Treatment for cancer frequently includes methodsDrugs that suppress the immune
system, which were initially … potential for obstructing these inhibitory pathways and boosting …

PPP2R1A mutations in uterine serous carcinoma: exploring the role and predictive marker potential of hotspot mutant p. R183W

M Remmerie - 2024 - lirias.kuleuven.be
2 天前 - … biomarkers to improve current treatment options. Remarkably, somatic … treatment
with PP2A activators as well as inhibitors, depending on the type of anti-cancer compound