… or indirect anti-tumor mechanism is classified and summarized, including inhibition of sputum,
… 细胞周期蛋白依赖性激酶(cyclin-dependent kinases, CDKs)是目前研究 的热点,它可以在细胞…

… 激酶抑制因子2A (cyclin-dependent kinase inhibitor 2A,CDKN2A)及… Statins exert anti-tumor
effects and improve the … and enhance the anti-tumor effects of chemotherapy drugs, and …

… , cell-cycle therapeutics also trigger anti-tumor immunity, regulate … (EGFR) inhibitors, and
autophagy inhibitors provide new … 过去的20年 里,细胞周期素依赖性激酶(cyclin-dependent kinas…

… of cyclin-dependent kinase 2, and dephosphorylation of retinoblastoma substrate42 … -dependent
cell-mediated cytotoxicity and direct anti-tumor effect via p27 kip1 accumulation43 …

… to exhibit anti-tumor … in Cyclin dependent kinases inhibitors (p21, and/or p27). In summary,
these findings suggest that DIM may be a potential chemopreventive and therapeutic agent …

… At present, a number of molecularly targeted anti-tumor drugs … the molecularly targeted
anti-tumor drugs derived from natural … Recent advances in cyclin-dependent kinase inhibitors with …

… mediator of cell death (Bim), cyclin-dependent kinase 4(CDK4), transforming growth factor β
… -related proteins, so inhibitors targeting the core particle show a good anti-tumor effect. This …

… cancer and the continuous development of anti-tumor drugs, the survival time of breast …
who have failed treatment with cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors. Novel anti-…

… Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are cell-targeted agents, and their
combination with endocrine therapy agents … Although CDK4/6 inhibitors have been well used in …

… of single agent neoadjuvant therapy with CDK4/6 inhibitor in … marker of cyclindependent
kinase 4/6 inhibition in patients with … A phase I study of the cyclin-dependent kinase 4/6 inhibitor …