Inhibitory Activity against Urease of Quercetin Glycosides Isolated from Allium cepa and Psidium guajava

S Shabana, A Kawai, K Kai, K Akiyama… - Bioscience …, 2010 - Taylor & Francis
S Shabana, A Kawai, K Kai, K Akiyama, H Hayashi
Bioscience, biotechnology, and biochemistry, 2010Taylor & Francis
Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity
against Jack bean urease. Quercetin-4′-O-β-d-glucopyranoside was isolated from Allium
cepa as a urease inhibitor with an IC50 value of 190 μm-. Quercetin and two quercetin
glycosides, avicularin and guaijaverin, were isolated from Psidium guajava as urease
inhibitors with respective IC50 values of 80 μm-, 140 μm-, and 120 μm-.
Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4′-O-β-D-glucopyranoside was isolated from Allium cepa as a urease inhibitor with an IC50 value of 190 μM-. Quercetin and two quercetin glycosides, avicularin and guaijaverin, were isolated from Psidium guajava as urease inhibitors with respective IC50 values of 80 μM-, 140 μM-, and 120 μM-.
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