Initiating exercise training in late middle age minimally protects muscle contractile function and increases myocyte oxidative damage in senescent rats
MM Thomas, W Khan, AC Betik, KJ Wright… - Experimental …, 2010 - Elsevier
Age-related loss of muscle mass and function exhibits a marked acceleration from late
middle age to senescence and exercise training is one method that has been proposed to
slow this process. The purpose of this study was to determine if long-term treadmill exercise
training initiated at late middle age could increase endogenous antioxidant enzyme activity
and attenuate the loss of skeletal muscle contractile properties in the gastrocnemius/
plantaris (GAS/Plan) and soleus (SOL) muscles of senescent rats (34–36mo) through a …
middle age to senescence and exercise training is one method that has been proposed to
slow this process. The purpose of this study was to determine if long-term treadmill exercise
training initiated at late middle age could increase endogenous antioxidant enzyme activity
and attenuate the loss of skeletal muscle contractile properties in the gastrocnemius/
plantaris (GAS/Plan) and soleus (SOL) muscles of senescent rats (34–36mo) through a …
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