Our understanding of alcohol use disorder (AUD), particularly alcohol's effects on the nervous
system, has unquestionably benefited from the use of model systems such as Drosophila …

… Behavioral studies of acute ethanol intoxication in Drosophila began in the late 1980s. The
… that are feasible in Drosophila should continue to provide novel insights into the mechanisms …

… ) requires increasing amounts of alcohol to become intoxicated in the future (see Figure 2). …
insight are more limited in mammalian models than invertebrates. Therefore, Drosophila are …

… underlying ethanol intoxication and tolerance. We demonstrate that flies intoxicated intermittently
… We would also like to thank the insightful feedback from anonymous reviewers of our …

… gain insights into the more complex process of alcohol addiction. Drosophila melanogaster
is … in biology and has provided essential insights into developmental and cellular processes …

… In this paper we review studies in Drosophila melanogaster that model different aspects of
natural and drug rewards, with an emphasis on how motivational states shape the value of the …

… 20 years using Drosophila melanogaster (Drosophila) and … Next, we will provide insight
into paradigms used to measure … Upon EtOH exposure, flies show signs of intoxication similar …

… In this review, we highlight the utility of Drosophila as a model for … insight into some
advantages and limitations of these approaches. Overall, this review demonstrates how Drosophila …

… Mode of exposure of neurotoxicant to Drosophila melanogaster. Any developmental stage
of Drosophila can be used for exposure to neurotoxicants. (A) Adult flies are exposed to the …

… , and we discuss how we can gain insight from studies in Drosophila. We focus on a few …
flies acquire resistance to the effect of ethanol intoxication. This tolerance is an adaptation in the …