Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment

FC Yang, YL Chen, SL Tang, CP Yu, PH Wang… - The ISME …, 2016 - academic.oup.com
Steroid hormones, such as androgens, are common surface-water contaminants. However,
literature on the ecophysiological relevance of steroid-degrading organisms in the
environment, particularly in anoxic ecosystems, is extremely limited. We previously reported
that Steroidobacter denitrificans anaerobically degrades androgens through the 2, 3-seco
pathway. In this study, the genome of Sdo. denitrificans was completely sequenced.
Transcriptomic data revealed gene clusters that were distinctly expressed during anaerobic …

Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment.

YFC Yang FuChun, CYL Chen YiLung… - 2016 - cabidigitallibrary.org
Steroid hormones, such as androgens, are common surface-water contaminants. However,
literature on the ecophysiological relevance of steroid-degrading organisms in the
environment, particularly in anoxic ecosystems, is extremely limited. We previously reported
that Steroidobacter denitrificans anaerobically degrades androgens through the 2, 3-seco
pathway. In this study, the genome of Sdo. denitrificans was completely sequenced.
Transcriptomic data revealed gene clusters that were distinctly expressed during anaerobic …
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