[HTML][HTML] Interactome-based approaches to human disease

M Caldera, P Buphamalai, F Müller… - Current Opinion in Systems …, 2017 - Elsevier
Recent advances in high-throughput technologies have created exciting opportunities for
systematically investigating the molecular basis of human disease. In addition to a growing
catalog of disease-associated genetic variations, we can now map out an increasingly
detailed network diagram of the complex machinery of interacting molecules that constitutes
the basis of (patho-) physiological states. The emerging field of 'network medicine'applies
tools and concepts from network theory to interpret this diagram and elucidate the relation …
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