… and repair mechanisms. Together, our results indicate that interference with hemozoin
formation is a valid chemotherapeutic target for development of new schistosomicidal agents. …

… , interference with hemozoin formation induced by these drugs represents an important
mechanism against … A recent study indicated that in a murine model of schistosomiasis, SmHz …

… and repair mechanisms. Together, our results indicate that interference with hemozoin
formation is a valid chemotherapeutic target for development of new schistosomicidal agents. …

… by mefloquine, the exact drug action mechanism against schistosomes is still unclear. … of
heme crystallization represents an attractive target, and interference with hemozoin formation in …

… Schistosomiasis is among the most neglected tropical diseases, since its mode of spreading
… So, we decided to further evaluate their reactivity toward hemozoin, and also to attempt to …

… schistosomiasis is less justified by the risk of drug resistance than by the fact that this drug is
… and Schistosoma due to interference with the formation of hemozoin. Various drugs besides …

… schistosomicidal mechanism of action of mefloquine is not known, the authors suggest that
the drug interferes … fact that the process of haemozoin formation is unique to the parasite, this …

… interference with Hz formation in S. mansoni represents an important mechanism of
schistosomicidal … crystallization process as a valid chemotherapeutic target to treat …

… is detoxified through aggregation, forming hemozoin (Hz). … mansoni is the main causative
agent of human schistosomiasis, … of males is very low, and CLQ did not interfere with heme …

… interference with the process of hemozoin formation. In the present review we explore what
is known about hemozoin… and notions of the possible mechanisms that could kill the parasite …