[HTML][HTML] Intracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies
OBJECTIVE: To test a newly invented intracytoplasmic sperm injection (ICSI) sperm
selection method based on sperm hyaluronic acid (HA) binding. DESIGN: Comparison of
chromosomal disomy and diploidy frequencies in sperm arising from semen and in HA-
bound sperm. SETTING: Academic andrology laboratory. PATIENT (S): Men presenting for
semen analysis. INTERVENTION (S): Washed sperm fractions of 32 semen samples were
applied to Petri dishes or glass slides coated with immobilized HA. The unbound sperm …
selection method based on sperm hyaluronic acid (HA) binding. DESIGN: Comparison of
chromosomal disomy and diploidy frequencies in sperm arising from semen and in HA-
bound sperm. SETTING: Academic andrology laboratory. PATIENT (S): Men presenting for
semen analysis. INTERVENTION (S): Washed sperm fractions of 32 semen samples were
applied to Petri dishes or glass slides coated with immobilized HA. The unbound sperm …