Intraocular lens as a drug delivery reservoir
… In this review, we discuss the development and the current knowledge on the applications
of IOLs as drug delivery reservoirs. … Hence, it is crucial to understand the pharmacokinetics
and to determine the drug concentration of loading as well as the optimum drug release
period when designing an IOL drug delivery reservoir. For an antibiotic-loaded IOL, the …
This study demonstrates the feasibility of the intraocular lens polymeric drug delivery
device providing effective treatments for the induced intraocular infection in a rabbit model. …
of IOLs as drug delivery reservoirs. … Hence, it is crucial to understand the pharmacokinetics
and to determine the drug concentration of loading as well as the optimum drug release
period when designing an IOL drug delivery reservoir. For an antibiotic-loaded IOL, the …
This study demonstrates the feasibility of the intraocular lens polymeric drug delivery
device providing effective treatments for the induced intraocular infection in a rabbit model. …
Summary
The use of IOLs as drug delivery reservoirs appears to show great promise. Although excellent results with therapeutic potential have been reported in experimental animal studies, further studies are needed to reach clinical use.
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