Involvement of glucagon in preventive effect of menthol against high fat diet induced obesity in mice

P Khare, P Mangal, RK Baboota, S Jagtap… - Frontiers in …, 2018 - frontiersin.org
… receptor antagonist, L-168,049, indicating that menthol-induced increase in serum glucagon
is … glucagon plays an important role in the preventive effect of menthol against HFD-induced

Menthol to induce non-shivering thermogenesis via TRPM8/PKA signaling for treatment of obesity

OD Sanders, JA Rajagopal… - Journal of obesity & …, 2020 - pmc.ncbi.nlm.nih.gov
… clustering around lipid droplets independent of genes involved in … and topical menthol or
icilin increased serum glucagon level via … food intake in a murine model of diet-induced obesity. …

The beneficial effects of essential oils in anti-obesity treatment

A De Blasio, A D'Anneo, M Lauricella… - International Journal of …, 2021 - mdpi.com
… plays a central role in the regulation of food intake by means of … included leptin,
catecholamines, glucagon, growth hormones (GH), … This has been correlated with a high fat diet of …

Combination of TRP channel dietary agonists induces energy expending and glucose utilizing phenotype in HFD-fed mice

J Kaur, V Kumar, V Kumar, S Shafi, P Khare… - … Journal of Obesity, 2022 - nature.com
… The transient receptor potential (TRP) channels are involved … w/v) menthol was found to
increase serum glucagon levels, … and peripheral insulin action in diet-induced obesity model of …

Protective effects of menthol against olanzapine-induced metabolic alterations in female mice

RK Sodhi, H Kumar, R Singh, Y Bansal… - European Journal of …, 2024 - Elsevier
… TRPM8 activation by menthol is also reported to alleviate high fat diet-induced obesity in …
role of TRPM8 channels in olanzapine-induced metabolic alterations in female balb/c mice. …

Antihypertrophic Effect of Menthol from Mentha x Piperita Concerning Cardiac Hypertrophy: A Review

A Nagarajan, VA Doss - The Natural Products Journal, 2023 - ingentaconnect.com
glucagon plays a significant role in the preventive effect of menthol (as TRPM8 modulator)
against a high-fat diet … is primarily involved in the effect of dietary menthol because TRPA1 …

MLR-1023 treatment in mice and humans induces a thermogenic program, and menthol potentiates the effect

CJ Rebello, AA Coulter, AG Reaume, W Cong… - Pharmaceuticals, 2021 - mdpi.com
Diet-induced obesity (CD1/ICR) and type 2 diabetes (db/db) … human models suggest a role
for menthol in the stimulation of … transporter 2 (SGLT2) inhibitors and glucagon-like-peptide-1 (…

Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome

D Bagetta, A Maruca, A Lupia, F Mesiti… - European Journal of …, 2020 - Elsevier
… positive results in the prevention of cardiovascular diseases (… Below, we reported the
involvement of olive oil and other … /day x 17 weeks) prevents HFD-induced obesity [48]. Again, in …

Topical menthol, a pharmacological cold mimic, induces cold sensitivity, adaptive thermogenesis and brown adipose tissue activation in mice

P Sankina, R Lal, P Khare… - … , Obesity and …, 2024 - Wiley Online Library
… tissue (WAT) ‘browning’ in normal and diet-induced obese mice. Topical application of …
insulin and glucagon levels, and the plasma insulin-glucagon ratio, to evaluate their role in …

… -mediated dissolving hydrogel that can sustainably release cold-mimetic menthol to induce adipocyte browning for treating obesity and its related metabolic disorders

T Ruan, CY Fu, CH Lin, KC Chou, YJ Lin - Biomaterials, 2023 - Elsevier
… Current clinical approaches to tackling obesity include surgical intervention and … induced
obese mice reportedly mimics that caused by exposure to cold. However, cold-mimetic menthol