Ion conductance channels of bilayer from sarcoma-45 phospholipids
UZ Mirkhodzhaev, VA Boldyrev… - Biofizika, 1989 - europepmc.org
UZ Mirkhodzhaev, VA Boldyrev, AK Tashmukhamedova, VP Tatarskiĭ, IN Dimant
Biofizika, 1989•europepmc.orgProperties of black bilayer membranes formed from sarcoma-45 phospholipids differed from
those of normal cell phospholipids bilayers. Two types of Ca2+-channels were discovered:
those multiple to 35 pA and those multiple to 90 pA. The study of bilayers from phospholipids
of nuclei, mitochondria, microsomal fractions showed that Ca2+-channels were localized in
the microsomal fraction of transformed cells. The relationship between DB18C6
diacetylderivatives membrane activity and their effect to growth of sarcoma-45 in vivo was …
those of normal cell phospholipids bilayers. Two types of Ca2+-channels were discovered:
those multiple to 35 pA and those multiple to 90 pA. The study of bilayers from phospholipids
of nuclei, mitochondria, microsomal fractions showed that Ca2+-channels were localized in
the microsomal fraction of transformed cells. The relationship between DB18C6
diacetylderivatives membrane activity and their effect to growth of sarcoma-45 in vivo was …
Properties of black bilayer membranes formed from sarcoma-45 phospholipids differed from those of normal cell phospholipids bilayers. Two types of Ca2+-channels were discovered: those multiple to 35 pA and those multiple to 90 pA. The study of bilayers from phospholipids of nuclei, mitochondria, microsomal fractions showed that Ca2+-channels were localized in the microsomal fraction of transformed cells. The relationship between DB18C6 diacetylderivatives membrane activity and their effect to growth of sarcoma-45 in vivo was discovered: the Ca2+-channel blocker diacetyl-DB18C6 inhibited the transformed cells growth.
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