Irisin vs. Treadmill exercise in post myocardial infarction cardiac rehabilitation in rats

PS Hassaan, SZ Nassar, Y Issa, N Zahran - Archives of Medical Research, 2019 - Elsevier
Background Irisin is an exercise-induced myokine that could play a role in post-myocardial
infarction (MI) cardiac rehabilitation. Aim of the study We investigated the ability of
dihydromyricetin to mimic the effects of exercise on raising serum irisin and on enhancing
cardiac function and remodeling following MI in rats. Methods MI was induced in albino rats
by subcutaneous injection of isoproterenol (85 mg/kg) for 2 consecutive days at an interval
of 24 h. One week post-MI, rats either underwent physical exercise by running on a motor …
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