Iron overload alters glucose homeostasis, causes liver steatosis, and increases serum triacylglycerols in rats

M Silva, ME Silva, H de Paula, CM Carneiro… - Nutrition research, 2008 - Elsevier
The objective of this study was to investigate the effect of iron overload with a hyperlipidemic
diet on the histologic feature of hepatic tissue, the lipid and glycemic serum profiles, and the
markers of oxidative damage and stress in a rat model. Twenty-four male Fischer rats,
purchased from Experimental Nutrition Laboratory, Federal University of Ouro Preto, were
assigned to 4 equal groups, 2 were fed a standard cholesterol-free diet (group C or control
and CI or control with iron) containing 8.0% soybean oil and 2 were fed a hyperlipidemic diet …
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