Ketamine

B Sinner, BM Graf - Modern anesthetics, 2008 - Springer
… so ketamine is also recommended for post-operative analgesia and sedation. The combination
of ketamine … In the treatment of chronic pain ketamine is effective as a potent analgesic or …

Ketamine use: a review

CJA Morgan, HV Curran… - …, 2012 - Wiley Online Library
Aims Ketamine remains an important medicine in both specialist anaesthesia and aspects
of pain management. At the same time, its use as a recreational drug has spread in many …

Ketamine and ketamine metabolite pharmacology: insights into therapeutic mechanisms

P Zanos, R Moaddel, PJ Morris, LM Riggs… - Pharmacological …, 2018 - ASPET
… targets of ketamine and its metabolites to the clinical effects of the drug. Ketamine metabolites
… Overall, pharmacological target deconvolution of ketamine and its metabolites will provide …

Ketamine

A Pai, M Heining - … Education in Anaesthesia, Critical Care & …, 2007 - academic.oup.com
Ketamine increases cerebral metabolism, … )-ketamine on ICP is not yet known. The
response of cerebral autoregulation to racemic ketamine has not yet been studied, but S-(+)-ketamine

Ketamine for depression: where do we go from here?

M Aan Het Rot, CA Zarate Jr, DS Charney… - Biological psychiatry, 2012 - Elsevier
… It has been more than a decade since ketamine, an anesthetic medication… ketamine may
relieve depressive symptoms within hours. This added to preclinical work suggesting ketamine's

Ketamine: 50 years of modulating the mind

L Li, PE Vlisides - Frontiers in human neuroscience, 2016 - frontiersin.org
Ketamine remains invaluable to the fields of … role for ketamine in treatment of refractory
depression and Post-Traumatic Stress Disorder. In this article, we review the history of ketamine, …

Ketamine and depression: a narrative review

A Corriger, G Pickering - Drug design, development and therapy, 2019 - Taylor & Francis
… However, there is a lack of data concerning ketamine with repeated administration at higher
doses. The clinical use of ketamine is increasing. Intranasal (S)-ketamine has recently been …

Ketamine: from medicine to misuse

K Wolff, AR Winstock - CNS drugs, 2006 - Springer
ketamine, an anaesthetic derivative of phencyclidine that has dissociative, analgesic and
psychedelic properties. Ketamine … While ketamine use in medical and veterinary settings is well …

Psychiatric safety of ketamine in psychopharmacology research

…, DC D'Souza, Yale Ketamine Study Group - …, 2007 - Springer
… dose of active ketamine. Eight hundred and thirty three active ketamine and 621 placebo …
subjects/infusions that were deemed related to ketamine administration (2% of subjects, 1.45% …

[PDF][PDF] Ketamine: its mechanism (s) of action and unusual clinical uses.

K Hirota, DG Lambert - British journal of anaesthesia, 1996 - researchgate.net
… agents, ketamine does not interact with GABA receptors16. Clinically, ketamine is administered
… pharmacological targets for ketamine and discuss the unusual clinical uses of this agent. …