Large volume fluid resuscitation for severe acute pancreatitis is associated with reduced mortality: a multicenter retrospective study
T Yamashita, M Horibe, M Sanui, M Sasaki… - Journal of clinical …, 2019 - journals.lww.com
Methods: We conducted a multicenter retrospective study at 44 institutions in Japan.
Inclusion criteria were age 18 years or older, and diagnosed with SAP from 2009 to 2013.
Patients were stratified into 2 groups: administered fluid volume< 6000 and≥ 6000 mL in
the first 24 hours. We evaluated the association between the 2 groups and clinical outcomes
using multivariable logistic regression analysis. The primary outcome was in-hospital
mortality. Secondary outcomes included the incidence of pancreatic infection and the need …
Inclusion criteria were age 18 years or older, and diagnosed with SAP from 2009 to 2013.
Patients were stratified into 2 groups: administered fluid volume< 6000 and≥ 6000 mL in
the first 24 hours. We evaluated the association between the 2 groups and clinical outcomes
using multivariable logistic regression analysis. The primary outcome was in-hospital
mortality. Secondary outcomes included the incidence of pancreatic infection and the need …
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