Neuroimaging studies have demonstrated that the right temporoparietal junction (TPJ) is
activated during detection of salient stimuli, including pain, in the sensory environment.
Right TPJ damage more often produces spatial neglect than left TPJ damage. We recently
reported a right lateralized system of white matter connectivity of the TPJ. However,
lateralization in intrinsic TPJ functional connectivity during a task/stimuli-independent state
has not been fully characterized. Here we used resting-state functional MRI in healthy …

Downar et al., 2003). Stimulus-driven activations of the right TPJ are typically reported
together 53 with responses in other ventral regions in the right hemisphere, most commonly
the anterior 54 insula (aINS) and inferior frontal gyrus (IFG), suggesting that these regions
encompass a right-55 lateralized “ventral attention network”(Corbetta et al., 2008). Regions
within the ventral 56 attention network also encode the prolonged salience of pain (Downar
et al., 2003) and show 57 remarkable overlap with the primary regions that are damaged in …