过去一年中添加的文章,按日期排序
Multi-omics Mendelian randomization integrating GWAS, eQTL and pQTL data revealed GSTM4 as a potential drug target for migraine
X Sun, B Chen, Y Qi, M Wei, W Chen, X Wu… - The Journal of …, 2024 - Springer
9 天前 - … Thus, we aimed to find the drug targets that improve the prognosis of … linkage
disequilibrium with one another, we also conducted colocalization and HEIDI tests. Target genes …
disequilibrium with one another, we also conducted colocalization and HEIDI tests. Target genes …
Genome wide association study gateway—transitioning variants from association to causality in complex diseases
C Zhao - Sleep, 2024 - academic.oup.com
20 天前 - … rare Mendelian diseases to common complex diseases, the search for disease-causing …
causal variants from non-causal proxies in linkage disequilibrium (LD), increasing the …
causal variants from non-causal proxies in linkage disequilibrium (LD), increasing the …
Microbiological and functional traits of peri-implant mucositis and correlation with disease severity
Z Feng, J Zhu, L Zhang, C Li, D Su, H Wang, Y Yu… - mSphere, 2024 - journals.asm.org
22 天前 - … microbial dysbiosis, functional potential, and disease severity. With the help of
metagenomic sequencing, we find the positive correlations between microbial dysbiosis, genus …
metagenomic sequencing, we find the positive correlations between microbial dysbiosis, genus …
[PDF][PDF] P-284 Large-scale genome-wide association study (GWAS) to determine the genetic underpinnings of female genital tract polyps (FGT)
A Pathare, N Pujol-Gualdo, V Rukins… - Human …, 2024 - academic.oup.com
30 天前 - … gold standard in complex disease genetics, has never been used to uncover the
genetics of the … To determine associations with other phenotypes, we performed a look-up of …
genetics of the … To determine associations with other phenotypes, we performed a look-up of …
AB0418 AN IMMUNOGENETIC STUDY OF AN INDIAN COHORT OF PSORIATIC ARTHRITIS PATIENTS WITH REFERENCE TO THEIR PHENOTYPE
M Shah, SK Upadhyaya, R Handa, SJ Gupta… - 2024 - ard.bmj.com
60 天前 - … *06 positivity, raising the possibility of linkage disequilibrium. There was a trend
of HLA-… and look for the influence of HLA alleles on the clinical expression of the disease. …
of HLA-… and look for the influence of HLA alleles on the clinical expression of the disease. …
GWAS Gateway–Transitioning Variants from Association to Causality in Complex Diseases [Commentary on Perturbation of the insomnia WDR90 GWAS locus …
C Zhao - Sleep, 2024 - academic.oup.com
76 天前 - … diseases to common complex diseases, the search for … from non-causal proxies in
linkage disequilibrium (LD), … , or deletions with a large impact on gene function [6]. The next …
linkage disequilibrium (LD), … , or deletions with a large impact on gene function [6]. The next …
Engineering computational single-cell and CRISPR-based functional genomics tools to study dynamic gene regulation in hematopoietic development and disease
ME Vinyard - 2024 - dash.harvard.edu
79 天前 - … The final chapter of this thesis presents a forward-looking perspective on how
future generations of deep learning models might be employed to study biology. It envisions a …
future generations of deep learning models might be employed to study biology. It envisions a …
[HTML][HTML] Structural and genetic diversity in the secreted mucins, MUC5AC and MUC5B
EG Plender, T Prodanov, PH Hsieh, E Nizamis… - bioRxiv, 2024 - ncbi.nlm.nih.gov
133 天前 - … We find that human MUC5B is largely invariant (5761–5762aa); … gene models,
suggesting a reduction in protein length during recent human evolution. Linkage disequilibrium (…
suggesting a reduction in protein length during recent human evolution. Linkage disequilibrium (…
[HTML][HTML] Redefining Aging as' Meta-Chronicity': Unveiling the Enduring Essence of Age-Related Health
S Ghaderzadeh, J Caldwell - Adv Clin Med Res, 2024 - genesispub.org
Large-scale genome-wide association study to determine the genetic underpinnings of female genital tract polyps
ADS Pathare, N Pujol-Gualdo, V Rukins, J Džigurski… - medRxiv, 2024 - medrxiv.org
183 天前 - … gold standard in complex disease genetics, has never been used to uncover the
genetics of the … To determine associations with other phenotypes, we performed a look-up of …
genetics of the … To determine associations with other phenotypes, we performed a look-up of …