Liver enzymes and risk of cardiovascular disease in the general population: a meta-analysis of prospective cohort studies

SK Kunutsor, TA Apekey, H Khan - Atherosclerosis, 2014 - Elsevier
Background Gamma glutamyltransferase (GGT), alanine aminotransferase (ALT), aspartate
aminotransferase (AST) and alkaline phosphatase (ALP), commonly used markers of liver
dysfunction, have been implicated with risk of cardiovascular disease (CVD). However, the
strength and consistency of their associations in the general population have not been
reliably quantified. Methods We synthesized available prospective epidemiological data on
the associations of baseline levels of GGT, ALT, AST, and ALP with CVD [composite CVD …
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