Local control and toxicity of multilevel spine stereotactic body radiotherapy
WH Beeler, KA Speth, MT Broderick, NK Jairath… - …, 2020 - journals.lww.com
BACKGROUND Spine stereotactic body radiotherapy (sSBRT) is commonly limited to 1 or 2
vertebral levels given a paucity of efficacy and toxicity data when more than 2 levels are
treated. OBJECTIVE To prove our hypothesis that multilevel sSBRT could provide similar
rates of local control (LC)(primary endpoint) and toxicity as single-level treatment using the
same clinical target, planning target, and planning organ-at-risk volumes. METHODS We
analyzed consecutive cases of sSBRT treated from 2013 to 2017. Time-to-event outcomes …
vertebral levels given a paucity of efficacy and toxicity data when more than 2 levels are
treated. OBJECTIVE To prove our hypothesis that multilevel sSBRT could provide similar
rates of local control (LC)(primary endpoint) and toxicity as single-level treatment using the
same clinical target, planning target, and planning organ-at-risk volumes. METHODS We
analyzed consecutive cases of sSBRT treated from 2013 to 2017. Time-to-event outcomes …
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