Local intramuscular transplantation of autologous mononuclear cells for critical lower limb ischaemia
K Moazzami, R Majdzadeh… - Cochrane Database of …, 2011 - cochranelibrary.com
K Moazzami, R Majdzadeh, S Nedjat
Cochrane Database of Systematic Reviews, 2011•cochranelibrary.comBackground Peripheral arterial disease (PAD) is a major health problem and in about 1% to
2% of patients the disease progresses to critical limb ischaemia (CLI). In a substantial
number of patients with CLI, no effective treatment option other than amputation is available
and around a quarter of these patients will require a major amputation during the following
year. Objectives To determine the effectiveness and safety of autologous adult bone marrow
derived mononuclear cells (BMMNCs) as a treatment for CLI.
2% of patients the disease progresses to critical limb ischaemia (CLI). In a substantial
number of patients with CLI, no effective treatment option other than amputation is available
and around a quarter of these patients will require a major amputation during the following
year. Objectives To determine the effectiveness and safety of autologous adult bone marrow
derived mononuclear cells (BMMNCs) as a treatment for CLI.
Background
Peripheral arterial disease (PAD) is a major health problem and in about 1% to 2% of patients the disease progresses to critical limb ischaemia (CLI). In a substantial number of patients with CLI, no effective treatment option other than amputation is available and around a quarter of these patients will require a major amputation during the following year.
Objectives
To determine the effectiveness and safety of autologous adult bone marrow derived mononuclear cells (BMMNCs) as a treatment for CLI.
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