Longitudinal metabolomics of human plasma reveals prognostic markers of COVID-19 disease severity

M Sindelar, E Stancliffe, M Schwaiger-Haber… - Cell Reports …, 2021 - cell.com
… early in the disease course, when clinical management is most effective. To aid in …
prognostic classification of disease severity, we perform untargeted metabolomics on plasma

Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcome

I Roberts, M Wright Muelas, JM Taylor, AS Davison… - Metabolomics, 2022 - Springer
serum metabolome in the longitudinal data of 28 severe patients. Our aim was to find not
only prognostic markers of subsequent disease severity … commercial pooled human serum (…

[HTML][HTML] Longitudinal Metabolomics Reveals Metabolic Dysregulation Dynamics in Patients with Severe COVID-19

R Uchimido, K Kami, H Yamamoto, R Yokoe, I Tsuchiya… - Metabolites, 2024 - mdpi.com
… of disease severity [55]. Future multicenter metabolomics studies on severe COVID-19 are
… Second, our samples, which were only from severe COVID-19 patients with mechanical …

Metabolomics in the Diagnosis and Prognosis of COVID-19

MR Hasan, M Suleiman, A Perez-Lopez - Frontiers in Genetics, 2021 - frontiersin.org
… , plasma samples from COVID-19 patients collected over six longitudinal time points were
analyzed for metabolomicrevealing 25 robust predictor metabolites for disease severity. In …

[HTML][HTML] Early Metabolomic and Immunologic Biomarkers as Prognostic Indicators for COVID-19

Z Chen, E Fung, CK Wong, L Ling, G Lui, CKC Lai… - Metabolites, 2024 - mdpi.com
… The effect size of disease severity on metabolome … and has been used by a number of
large-scale longitudinal cohort … platforms may reveal additional non-lipid metabolomic shifts …

Diagnostic, prognostic and mechanistic biomarkers of COVID-19 identified by mass spectrometric metabolomics

M Bourgin, S Durand, G Kroemer - Metabolites, 2023 - mdpi.com
… in longitudinal studies across various COVID-19 waves [44]. … infected-subjects and 120
healthy controls, revealing that the … that correlate with COVID-19 disease severity and viral SARS…

Metabolomic profiling of plasma reveals differential disease severity markers in COVID-19 patients

LB Oliveira, VI Mwangi, MA Sartim, J Delafiori… - Frontiers in …, 2022 - frontiersin.org
… the disease by interconnecting several factors, primarily through analyzing the metabolomic
profile involved in COVID-19 severity … from other studies in which factors such as underlying …

A multi-omics longitudinal study reveals alteration of the leukocyte activation pathway in COVID-19 patients

K Suvarna, A Salkar, V Palanivel… - Journal of Proteome …, 2021 - ACS Publications
… et al. in their longitudinal targeted metabolomic study of serum samples … longitudinal study
identified the distinct proteomic and metabolomic profile for the prognosis of COVID-19 severity

The plasma metabolome of long COVID patients two years after infection

Y López-Hernández, J Monárrez-Espino, DAG López… - Scientific reports, 2023 - nature.com
revealed that 50% of analyzed plasma metabolites showed statistical differences between
COVID-19 and long COVID-19 … participants longitudinally surveyed before and after COVID-19

Metabolomics study of COVID-19 patients in four different clinical stages

A Valdés, LO Moreno, SR Rello, A Orduña… - Scientific reports, 2022 - nature.com
… /severe COVID-19 to severe condition 9 . Danlos et al. also reported alterations in the plasma
metabolome … This work also shows that metabolomics is a highly valuable resource for a …