Low prevalence of anti-HCV antibody among Italian children.

L Romanò, A Azara, M Chiaramonte, D De Mattia… - Infection, 1994 - europepmc.org
L Romanò, A Azara, M Chiaramonte, D De Mattia, A Giammanco, ME Moschen, B Scarpa…
Infection, 1994europepmc.org
The seroprevalence of anti-HCV antibody was studied among 2,749 children and teenagers
(1,438 males and 1,311 females) living in Italy. Anti-HCV antibody testing was positive by
both EIA and RIBA in ten (0.36%) subjects. The positivity rate increased with age, ranging
from 0 among children less than 6 years of age to 0.8% among those aged 17-19 years chi 2
linear regression= 0.038). Anti-HCV prevalence ranged from 0.2% in northeastern regions
and in Apulia to 0.6% in Sicily and Sardinia (p> 0.005), and no difference was seen between …
The seroprevalence of anti-HCV antibody was studied among 2,749 children and teenagers (1,438 males and 1,311 females) living in Italy. Anti-HCV antibody testing was positive by both EIA and RIBA in ten (0.36%) subjects. The positivity rate increased with age, ranging from 0 among children less than 6 years of age to 0.8% among those aged 17-19 years chi 2 linear regression= 0.038). Anti-HCV prevalence ranged from 0.2% in northeastern regions and in Apulia to 0.6% in Sicily and Sardinia (p> 0.005), and no difference was seen between males (0.35%, CI 95%: 0.04-0.66) and females (0.38%, CI 95%: 0.04-0.66)(Fisher's exact test= 0.565). From these data it appears that in Italy HCV infection is an uncommon event during childhood.
europepmc.org
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