Objective: Low tidal volume ventilation lowers mortality in the acute respiratory distress
syndrome. Previous studies reported poor low tidal volume ventilation implementation. We
sought to determine the rate, quality, and predictors of low tidal volume ventilation use.
Design: Retrospective cross-sectional study. Setting: One academic and three community
hospitals in the Chicago region. Patients: A total of 362 adults meeting the Berlin Definition
of acute respiratory distress syndrome consecutively admitted between June and December …

Acute Respiratory Distress Syndrome (ARDS) is a lifethreatening diagnosis that has been
extensively investigated. Previous data shows that low tidal volume ventilation (LTVV) with a
tidal volume of 6 mL/kg of predicted body weight (PBW) improves mortality in patients with
ARDS. However, despite its well-studied benefits in clinical trials such as the Acute
Respiratory Distress Syndrome Network (ARDSNet) trial, LTVV continues to be underutilized
in many medical centers. The goal of this study was to evaluate the use of LTVV in ARDS …