Lycopene differentially induces quiescence and apoptosis in androgen-responsive and-independent prostate cancer cell lines
BACKGROUND & AIMS: Lycopene has been credited with a number of health benefits
including a decrease in prostate cancer risk. Our study investigates the molecular
mechanism underlying anti-cancer activity of lycopene-based products in androgen-
responsive (LNCaP) and androgen-independent (PC3) cells. METHODS: The effect of
lycopene-based agents on prostate cancer growth and survival were examined using
proliferation assays, bromodeoxyuridine incorporation and flow cytometric analysis of …
including a decrease in prostate cancer risk. Our study investigates the molecular
mechanism underlying anti-cancer activity of lycopene-based products in androgen-
responsive (LNCaP) and androgen-independent (PC3) cells. METHODS: The effect of
lycopene-based agents on prostate cancer growth and survival were examined using
proliferation assays, bromodeoxyuridine incorporation and flow cytometric analysis of …