Background Periventricular leukomalacia (PVL) is the most common form of preterm brain
injury affecting the cerebral white matter. This type of injury involves a multiphase process
and is induced by many factors, including hypoxia–ischemia (HI) and infection. Previous
studies have suggested that lymphocytes play a significant role in the pathogenesis of brain
injury, and the aim of this study was to determine the contribution of lymphocyte subsets to
preterm brain injury. Methods Immunohistochemistry on brain sections from neonatal mice …