MYC protein expression is associated with poor prognosis in primary diffuse large B‐cell lymphoma of the central nervous system

G Tapia, MJ Baptista, AM Muñoz‐Marmol, A Gaafar… - Apmis, 2015 - Wiley Online Library
MYC and BCL2 gene translocations and protein expression have recently demonstrated to
be of prognostic significance in systemic diffuse large B‐cell lymphoma (DLBCL). However,
their role in primary central nervous system DLBCL (CNS‐DLBCL) prognosis has been
scarcely analyzed. We studied the immunophenotype, the status of the MYC, BCL2, and
BCL6 genes and the clinical features of a series of 42 CNS‐DLBCL and evaluated their
prognostic significance. We found high MYC protein expression in 43% of cases, and this …
被引用次数：38 相关文章 所有 7 个版本

MYC protein expression is associated with poor prognosis in diffuse large B cell lymphoma patients treated with RCHOP chemotherapy

M Zhou, J Wang, J Ouyang, J Xu, B Chen, Q Zhang… - Tumor Biology, 2014 - Springer
This study aims to investigate the prognostic significance of the MYC protein expression in
diffuse large B cell lymphoma (DLBCL) patients treated with RCHOP (rituximab plus
cyclophosphamide, doxorubicin, vincristine, and prednisone). A total of 60 patients with
DLBCL from 2008 to 2013 were included. Formalin-fixed, paraffin-embedded DLBCL
samples were analyzed for MYC protein expression and divided into high or low MYC
group. The MYC protein expression and the international prognostic variables were …
被引用次数：26 相关文章 所有 10 个版本
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