[HTML][HTML] Male C57BL/6J mice have higher presence and abundance of Borrelia burgdorferi in their ventral skin compared to female mice
CW Koloski, G Hurry, A Foley-Eby, H Adam… - Ticks and Tick-borne …, 2024 - Elsevier
Borrelia burgdorferi is a tick-borne spirochete that causes Lyme disease in humans. The
host immune system controls the abundance of the spirochete in the host tissues. Recent
work with immunocompetent Mus musculus mice strain C3H/HeJ found that males had a
higher tissue infection prevalence and spirochete load compared to females. The purpose of
this study was to determine whether host sex and acquired immunity interact to influence the
prevalence and abundance of spirochetes in the tissues of the commonly used mouse strain …
host immune system controls the abundance of the spirochete in the host tissues. Recent
work with immunocompetent Mus musculus mice strain C3H/HeJ found that males had a
higher tissue infection prevalence and spirochete load compared to females. The purpose of
this study was to determine whether host sex and acquired immunity interact to influence the
prevalence and abundance of spirochetes in the tissues of the commonly used mouse strain …
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