过去一年中添加的文章,按日期排序

Evobrutinib in multiple sclerosis: challenges and unmet goals

A van der Walt - The Lancet Neurology, 2024 - thelancet.com
2 天前 - … However, these therapies are less effective at preventing … cell maturation and
activation, cytokine production, and T … for new multiple sclerosis treatments that target disease

Targeting Myeloid-Derived Suppressor Cells to Enhance Immune Checkpoint Inhibitor Therapy

HD Savardekar - 2024 - rave.ohiolink.edu
2 天前 - effective therapeutic interventions are imperative in combating this complex
disease. Over … While it initially aids in promoting cytokine production and eliminating pre-malignant …

Long-Term Swimming Exercise Attenuates Right Ventricular Hypertrophy via Modulating Meta-inflammation in Monocrotaline-Induced Pulmonary Hypertensive Rats

Z Chen, J Wang, X Qin, N Di, H Deng, X Li - Biochemical and Biophysical …, 2024 - Elsevier
5 天前 - … , reduced serum inflammatory cytokines, and improved systemic and RV … is a
progressive chronic disease without an effective cure. Exercise has been shown to be beneficial

Cyanocobalamin-loaded dissolving microneedles diminish skin inflammation in vivo

…, HA Santos, AS Cordeiro, A Melero - Journal of controlled … - pubmed.ncbi.nlm.nih.gov
5 天前 - … therefore a reasonable therapeutic goal. Cyanocobalamin, … studies noted an
effective drug presence within the … , and decrease of inflammatory cytokines levels point out the …

Senoinflammation as the underlying mechanism of aging and its modulation by calorie restriction

SG Noh, HW Kim, S Kim, KW Chung, YS Jung… - Ageing Research …, 2024 - Elsevier
7 天前 - effective suppression of various pro-inflammatory … Furthermore, it serves as a
potential therapeutic target for … inflammatory environment include cytokines and chemokines, …

Investigating the Roles of BRD4 and PRMT5 in Acute Graft-versus-Host Disease

KJ Snyder - 2024 - rave.ohiolink.edu
8 天前 - … T cells which secrete inflammatory cytokines and carry out … their potential as novel
therapeutic targets for acute GVHD… acute GVHD while maintaining the beneficial graft-versus-…

Identifying Challenges After Chimeric Antigen Receptor (CAR) T-Cell Therapy: A Convergent Mixed Methods Study

KN MacDougall - 2024 - search.proquest.com
8 天前 - … potentially fatal condition of increased cytokine production … relapsed disease following
CAR-T cell therapy as the most … least helpful to most helpful (1 = least helpful, to 5 = most

IL-1β and vascular inflammation in hypertension and metabolic diseases?

AM Sivalingam, A Pandian - Hypertension Research, 2024 - nature.com
11 天前 - is critical for developing effective therapeutic techniques [1]. IL-1β is a proinflammatory
cytokine … both high blood pressure and metabolic problems, which include diabetes and …

Investigating Chemokine-Induced NF-κB Activation in Retinal Cells and Its Contribution to Age-Related Macular Degeneration Pathogenesis: A Systematic Review

I Siddiqui, NA Khan, F Ahmad, M Nawaz, A Naeem… - medRxiv, 2024 - medrxiv.org
13 天前 - … remains critical for developing effective therapies. This study … apoptosis through
enhanced cytokine production and reactive … therapeutic targets to mitigate disease progression. …

Comment on the role of interferons in the pathology of beta cell destruction in type 1 diabetes

S Lenzen - Diabetologia, 2024 - Springer
14 天前 - therapeutic concept into an effective translational therapy … cell infiltrate is a prominent
feature of the disease process [… Therefore, in conclusion, a proinflammatory cytokine that is