Mechanisms of Kaposis sarcomaassociated herpesvirus latency and reactivation

F Ye, X Lei, SJ Gao - Advances in virology, 2011 - Wiley Online Library
… of Kaposis sarcoma (KS). The mechanisms controlling KSHV latency and reactivation are
… Here, we review the cellular and molecular basis of KSHV latency and reactivation with a …

Reactivation and lytic replication of Kaposi's sarcoma-associated herpesvirus: an update

KK Aneja, Y Yuan - Frontiers in microbiology, 2017 - frontiersin.org
… However, latency can be disrupted and KSHV is reactivated for entry into the lytic replication…
initiation and regulation of KSHV reactivation and the mechanisms underlying the process of …

Kaposi's sarcoma and its associated herpesvirus

EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010 - nature.com
mechanisms through which KSHV can induce KS that have been gained in the past 16 years.
KSHV latent transcripts, such as latency-associated … the lytic reactivation of the virus, and …

Kaposi sarcoma herpesvirus pathogenesis

G Mariggio, S Koch, TF Schulz - … Transactions of the …, 2017 - royalsocietypublishing.org
… This role of the DDR is connected to ‘conventional’ mechanisms of innate immunity [270,271…
gene expression in order to facilitate reactivation of KSHV from latency [104]. In an …

Molecular mechanisms of Kaposi sarcoma development

A Karabajakian, I Ray-Coquard, JY Blay - Cancers, 2022 - mdpi.com
Kaposis sarcoma-associated herpes virus (KSHV) is the … establish a latent phase in host
cells in which latency proteins and … high levels of reactivation from latency occur before disease …

… of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latency

KE Lan, DA Kuppers, SC Verma, N Sharma… - Journal of …, 2005 - Am Soc Microbiol
… showed that LANA is capable of suppressing lytic reactivation and maintaining viral … In
summary, the mechanism by which KSHV can establish latency postinfection is still incomplete …

Reactivation and role of HHV-8 in Kaposi's sarcoma initiation

B Ensoli, M Stürzl, P Monini - 2001 - Elsevier
… virus escape mechanisms and deficient immune responses toward HHV-8, virus reactivation
and … due to reactivation of latent HHV-8 by the IC that are increased in KS. Evidence for this …

Virology, pathogenetic mechanisms, and associated diseases of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8)

R Sarid, A Klepfish, A Schattner - Mayo Clinic Proceedings, 2002 - Elsevier
… The latency is probably associated with the hematopoietic system. The mechanisms by …
immune system and the events leading to reactivation are incompletely understood. Although the …

Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis

TF Schulz, E Cesarman - Current opinion in virology, 2015 - Elsevier
… lytic reactivation; miR-K12-1 targets p21; miR-K12-5 reduces RTA expression to maintain
latency; miR-K12-7 reduces expression of NK cell ligand MICB; miR-K12-11 is orthologue of …

Kaposi's sarcomaassociated herpesvirus

PS Moore, Y Chang - Clinical Virology, 2009 - Wiley Online Library
… KSHV transmission and reactivation among transplant patients are also major preventable
… genome is believed to replicate through a rolling-circle mechanism from the circular latent ge…