Melatonin and aging: in vitro effect of young and mature ring dove physiological concentrations of melatonin on the phagocytic function of heterophils from old ring …

MP Terron, J Cubero, JM Marchena, C Barriga… - Experimental …, 2002 - Elsevier
We have studied the circadian rhythm of melatonin in the ring dove (Streptopelia risoria) for
different age groups: young (1–1.5 years), mature (3–4years) and old animals (> 8years).
Melatonin levels were determined by radioimmunoassay. Results showed a significant
decline in plasma melatonin levels in old animals when compared with the concentrations
observed in the other two age groups, in which maximum (nocturnal) concentrations were
300pg/ml and minimum (diurnal) concentrations were 50pg/ml. We analyzed the in vitro …
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