At a single evening dose of 5–10 mg, melatonin (MLT), the pineal gland hormone, can exert
a positive effect on the frequency of epileptic attacks in children with sleep disturbances of
various etiologies. We have shown that the sleep behavior can be normalized and an
existing epilepsy can be favorably influenced. Pretherapeutic MLT secretion profiles can
provide new information concerning the origin and treatment of these disturbances. In vitro
experiments suggest that this effect might be the result of the interaction between MLT and …

At a single evening dose of 5-10 mg, melatonin (MLT), the pineal gland hormone, can exert
a positive effect on the frequency of epileptic attacks in children with sleep disturbances of
various etiologies. We have shown that the sleep behavior can be normalized and an
existing epilepsy can be favorably influenced. Pretherapeutic MLT secretion profiles can
provide new information concerning the origin and treatment of these disturbances. In vitro
experiments suggest that this effect might be the result of the interac-tion between MLT and …