过去一年中添加的文章,按日期排序

LW-213, a derivative of wogonin, triggers reticulophagy-mediated cell death in NSCLC via lysosomal damage combined with NPC1 inhibition

H Wang, Y Jiang, M Zhu, H Li, H Chen, H Wang… - Phytomedicine, 2024 - Elsevier
71 天前 - … lysosomal membrane damage, thereby activating the phosphoinositide-… membrane
tethering and lipid transport (PITT) pathway. This activation promoted cholesterol transport

CHC22 clathrin recruitment to the early secretory pathway requires two-site interaction with SNX5 and p115

J Greig, GT Bates, DI Yin, K Briant, B Simonetti… - The EMBO …, 2024 - embopress.org
74 天前 - intracellular transport routes. CHC17 performs endocytosis and housekeeping
membrane … Our finding that SNX5 binds the ERGIC tether protein p115 expands this emerging …

Molecular and Cell Biological Investigations on the Determinants and Consequences of GAIN Domain Cleavage in Class B2/Adhesion G protein-coupled receptors

MPYK Chung - ul.qucosa.de
123 天前 - … the ER membrane, defining the importance of membrane proximity in the completion
of … of the GAIN domain, but also the membrane tethering property of the CTF, allowing a …

Triple-transformable dynamic surroundings for programmed transportation of bio-vulnerable mRNA payloads towards systemic treatment of intractable solid tumors

Y Wang, J Liu, H Cui, L Zhang, Z Li, X Wang, J Wang… - Biomaterials, 2024 - Elsevier
131 天前 - … cellular uptake and intracellular trafficking activities. … membranes, enabling
translocation into the cytosol. In this study, PEGylated mRNA delivery nanoparticulates were tethered

Function and regulation of Rab GTPases in cancers

S Xu, B Cao, G Xuan, S Xu, Z An, C Zhu, L Li… - Cell Biology and …, 2024 - Springer
183 天前 - intracellular membrane trafficking processes through the recruitment of effectors,
such as tethering … is the basic mechanism in intracellular transport. Generally speaking, sorting …

The Molecular mechanisms of aminergic release at type II synaptic terminals of Drosophila melanogaster and the effects of spermidine on mitochondrial redox status.

JCK See - 2024 - refubium.fu-berlin.de
186 天前 - … Synaptic vesicles must be tethered, primed, and then fused with the presynaptic
membrane to fulfil their purpose. This is orchestrated by a complex proteinaceous machinery at …

[HTML][HTML] VSI: The Anoctamins: Structure and Function:“Intracellular” anoctamins

K Kunzelmann, J Ousingsawat, R Schreiber - Cell Calcium, 2024 - Elsevier
198 天前 - … The PM-located Ca 2+ -activated Cl − channel ANO1, a homologue of yeast Ist2,
can also be regarded as a membrane tether given its direct interaction with the IP 3 R [5,102]. …

Anoctamins in epithelial transport

K Kunzelmann, J Ousingsawat, R Schreiber - Cell Calcium, 2024 - epub.uni-regensburg.de
198 天前 - … The PM-located Ca2+-activated Cl channel ANO1, a homologue of yeast Ist2, can
also be regarded as a membrane tether given its direct interaction with the IP3R [5,102]. In a …

TRAPPC11-CDG muscular dystrophy: Review of 54 cases including a novel patient

JR Corona-Rivera, I Martínez-Duncker… - Molecular genetics and …, 2024 - Elsevier
218 天前 - … functions as a tethering factor involved in intracellular trafficking. … , membrane
trafficking assays in our patient showed defective abnormal endoplasmic reticulum-Golgi transport

XPR1: a regulator of cellular phosphate homeostasis rather than a Pi exporter

D Burns, R Berlinguer-Palmini, A Werner - Pflügers Archiv-European …, 2024 - Springer
226 天前 - membrane and could potentially mediate Pi export; however, we found no evidence
of such transport … the core domain membrane tethering and membrane localization and the …