Membranoproliferative glomerulonephritis—a new look at an old entity
S Sethi, FC Fervenza - New England Journal of Medicine, 2012 - Mass Medical Soc
This review discusses the causes, pathogenesis, and clinical management of
membranoproliferative glomerulonephritis, which accounts for 7 to 10% of biopsy-confirmed
glomerulonephritis cases. Current classification reflects advances in the understanding of
this condition.
membranoproliferative glomerulonephritis, which accounts for 7 to 10% of biopsy-confirmed
glomerulonephritis cases. Current classification reflects advances in the understanding of
this condition.
Membranoproliferative glomerulonephritis
S Sethi, FC Fervenza - Core Concepts in Parenchymal Kidney Disease, 2013 - Springer
Membranoproliferative glomerulonephritis (MPGN), also known as mesangiocapillary
glomerulonephritis, is a pattern of glomerular injury that results from deposition of immune
complexes and/or complement in the mesangium and along the glomerular capillary walls.
Recently, a classification that emphasizes the pathogenesis of MPGN has been proposed.
According to this new classification, MPGN can be divided into immune complex-mediated
(Ig) or complement-mediated MPGN. The common causes of Ig-mediated MPGN include …
glomerulonephritis, is a pattern of glomerular injury that results from deposition of immune
complexes and/or complement in the mesangium and along the glomerular capillary walls.
Recently, a classification that emphasizes the pathogenesis of MPGN has been proposed.
According to this new classification, MPGN can be divided into immune complex-mediated
(Ig) or complement-mediated MPGN. The common causes of Ig-mediated MPGN include …
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