… of methionine oxidation in aging The singular importance of methionine oxidation in aging
… from trabecular meshwork increases from 10 to 40 during aging, over the range of 10 to 80 …

… Moreover, recent data show that methionine levels in tissue proteins negatively correlate …
lowering of methionine levels is involved in the control of mitochondrial oxidative stress and …

… oxidation), oxidation of methionine residues to methionine sulfoxide is reversible; thus, cyclic
oxidation and reduction of methionine … of proteins to oxidation. The importance of protein …

… between individual animals and methionine sulfoxides are enriched … methionine oxidation
in brains of old mice. Our results suggest that under normal conditions, methionine oxidation …

… oxidative stress is closely related to aging and impaired metabolic health and is influenced
by diet-derived nutrients and energy. Recent studies have shown that methionine … in oxidative …

… bacteria, yeast, and mammals is dependent on MsrA ability to reverse oxidized methionine.
In fact, methionine oxidation modulates the biological activity of some proteins, pointing to an …

… the capacity to lower mitROS generation and oxidative stress in response to MetR similarly
… reverse aging-related variations in oxidative stress. In this investigation the effects of aging …

… protease and the oxidized protein repair system methionine sulfoxide reductase in the
maintenance of mitochondrial protein homeostasis in the context of oxidative stress and aging. …

… This way of salvaging free methionine has a special importance under conditions of
oxidative stress that promote methionine oxidation. From accumulating recent evidences, it is …

… on positive effects of methionine restriction (MR) were first published in 1993. MR is a low-methionine
dietary intervention that has been reported to ameliorate aging and aging-related …