Method for optical coherence tomography imaging with molecular contrast

JA Izatt, DK Rao, C Yang, MA Choma… - US Patent …, 2006 - Google Patents
Spatial information, such as concentration and displace ment, about a speci? c molecular
contrast agent, may be determined by stimulating a sample containing the agent, thereby
altering an optical property of the agent. A plurality of optical coherence tomography (OCT)
images may be acquired, at least some of Which are acquired at di? cerent stimulus
intensities. The acquired images are used to pro? le the molecular contrast agent
concentration distribution of 24'2003' the sample.
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