Methods of using oligonucleotide-guided argonaute proteins
The invention relates to the use of Argonaute polypeptide: guide molecule complexes as fast
and specific nucleic acid probes, as specific, nucleic acid-guided restriction enzymes for
DNA and RNA substrates, and as a means to detect RNA-protein interactions, RNA
detection, DNA detection, and RNA depletion. Using Such Argonaute polypeptide: guide
molecule complexes enables fast and specific detec tion, purification, and enzymatic activity.
and specific nucleic acid probes, as specific, nucleic acid-guided restriction enzymes for
DNA and RNA substrates, and as a means to detect RNA-protein interactions, RNA
detection, DNA detection, and RNA depletion. Using Such Argonaute polypeptide: guide
molecule complexes enables fast and specific detec tion, purification, and enzymatic activity.
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