神经原纤维缠结形成的机制: 有助于开发其抑制剂

A Metaxas, SJ Kempf - 中国神经再生研究(英文版), 2016 - sjzsyj.com.cn
… involving protein phosphorylation and de-phosphorylation are … Extracellular tangles are
preferentially stained with … be also advantageous in relation to the bioinformatics analysis of …

磷酸化tau 作为突触线粒体中的毒剂: 对衰老和阿尔茨海默病的影响

AK Torres, BI Rivera, CM Polanco, C Jara… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… A clear relationship between phosphorylated tau and … Besides, methylation in specific residues,
such as K267 and … , because it prevents tau phosphorylation and aggregation (Funk et al.…

tau 蛋白与阿尔茨海默病的研究进展

胡江平, 耿瑞, 李凯军 - 中国康复理论与实践, 2014 - cjrtponline.com
… is neurofibrillary tangles in neurons, in which principal component is the phosphorylation of
… This paper reviewed the relationship between tau protein phosphorylation and Alzheimer's …

中药头顶一颗珠提取物可减轻tau 蛋白磷酸化异常

HB Luo, N Shang, WZ Xie, DJ Wen, M Qu… - 中国神经再生研究 …, 2018 - sjzsyj.com.cn
… the changes in methylated and demethylated PP2Ac levels … phosphorylation was increased
together with an increase of the inactivated form of PP2Ac due to increased phosphorylation

阿尔茨海默病中的Aβ 肽和tau 蛋白串扰

AR Roda, G Serra-Mir, L Montoliu-Gaya… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… aggregation in form of neurofibrillary tangles, and these aggregates lead … Phosphorylation
of tau negatively regulates its ability to interact with microtubules, but whether phosphorylation

由内含子保留引起的Tau 截断在阿尔茨海默病皮质中富集并表现出改变的生化特性

CT Ong - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… , changes in the level of phosphorylated Tau at threonine 181/217 in the blood plasma and
methylation. For instance, during granulocyte differentiation, binding of MeCP2 to methylated

肿瘤化疗药物引起的神经退行性变及海马功能障碍

M Yang, C Moon - 中国神经再生研究(英文版), 2013 - sjzsyj.com.cn
… to clarify the relationship between hippocampal neurogenesis and hippocampal dysfunction.
… Methotrexate decreases PP2A methylation and increases tau phosphorylation in neuron. …

DNA 甲基转移酶1 调节神经元的存活

J Symmank, G Zimmer - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
… are phospho-regulated, further studies determining the phosphorylation levels of relevant …
of an altered H3K4 methylation status in DNA methylation-independent transcriptional …

运动干预与阿尔茨海默病

D Li, J Jia, H Zeng, X Zhong, H Chen… - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… in the formation of neurofibrillary tangles, which block the … phosphorylated inositolrequiring
enzyme 1, phosphorylated … brain has lower DNA methylation levels at the apolipoprotein …

阿尔茨海默氏病: 两种疾病的故事?

E Nardini, R Hogan, A Flamier, G Bernier - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… Tauopathy in the Bmi1+/– mouse included p-Tau accumulation and large p-Tau deposits
in the cortex, whereas p-Tau tangles were not observed. Neurodegeneration is evidenced by …