[HTML][HTML] Methylation changes in mature sperm deoxyribonucleic acid from oligozoospermic men: assessment of genetic variants and assisted reproductive technology …
D Montjean, C Ravel, M Benkhalifa, P Cohen-Bacrie… - Fertility and sterility, 2013 - Elsevier
Objective To characterize a potential genetic cause for methylation errors described in
oligozoospermia. Design Analysis of PEG1/MEST-DMR and H19-DMR methylation level in
sperm, in parallel with the study of several genes on the Y chromosome, DNMT3A, and
DNMT3L. Clinical outcome was also looked at regarding PEG1/MEST-DMR and H19-DMR
methylation level in sperm. Setting Research and diagnostic laboratories. Patient (s) One
hundred nineteen normospermic and 175 oligozoospermic men consulting for couple …
oligozoospermia. Design Analysis of PEG1/MEST-DMR and H19-DMR methylation level in
sperm, in parallel with the study of several genes on the Y chromosome, DNMT3A, and
DNMT3L. Clinical outcome was also looked at regarding PEG1/MEST-DMR and H19-DMR
methylation level in sperm. Setting Research and diagnostic laboratories. Patient (s) One
hundred nineteen normospermic and 175 oligozoospermic men consulting for couple …