Although our knowledge about Brucella virulence factors and the host response increase
rapidly, the mechanisms of immune evasion by the pathogen and causes of chronic disease
are still unknown. Here, we aimed to investigate the immunological factors which belong to
CD8+ T cells and their roles in the transition of brucellosis from acute to chronic infection.
Using miRNA microarray, more than 2000 miRNAs were screened in CD8+ T cells of
patients with acute or chronic brucellosis and healthy controls that were sorted from …

Although our knowledge about Brucella virulence factors and the host response increase
rapidly, the mechanisms of immune evasion by the pathogen and causes of chronic disease
are still unknown. Here, we aimed to investigate the immunological factors which belong to
CD8+ T cells and their roles in the transition of brucellosis from acute to chronic infection.
Using miRNA microarray, more than 2000 miRNAs were screened in CD8+ T cells of
patients with acute or chronic brucellosis and healthy controls that were sorted from …