This paper addresses the problems in microwave non-linear measurements. It discusses techniques to synthesize loads, the most used non-linear measurement techniques, and harmonic load-pulling. An experimental setup for characterizing power amplifiers must be able to measure the complex spectrum of the waves at the amplifier ports as a function of frequency, input power, and source and load termination at the fundamental and harmonic frequencies. The vector network analyzer (VNA) is the core instrument used in the non-linear characterization scenario. The basic idea is to keep the operations of VNA/mixers linear, diverting to them only a small portion of the signal present at the device under test (DUT) ports, therefore keeping unaltered the VNA capabilities already exhibited for small signal measurements.