A novel structure to determine volume fraction of liquids present in microfluidic channel/tube with high accuracy is being presented. Such determination also known as compositional analysis is widely used in chemical, bio-medical, pharmaceutical and other applications/industries. Monitoring/measuring volume fraction of liquid in mixture through conventional methods is a time consuming task. Some quantity of liquid is also wasted in this process. Microwave technique using resonance method has eased such a task. Proposed split ball resonator structure removes these problems. Proposed structure can detect/sense complex permittivity of liquid mixture in microfluidic channel/tube. Basing upon this structure a model is being proposed to determine volume fraction of liquids. This model utilizes measured electrical quantities ie resonant frequency and quality factor of proposed structure. Compositional analysis of liquids can be done within fraction of a second without wasting time and material through proposed system.